Effects of aerobic endurance training on gas exchange kinetics of older men

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Abstract
The kinetics of gas exchange at the on-transient of exercise are appreciably slowed in older individuals. Eight older men (72 yr) completed 6 months of aerobic cycle training. Ventilation and gas exchange kinetics were determined at the onset of a below threshold (ventilatory threshold, VET) square wave exercise function and compared with control values (N = 4, age 70 yr). Gas exchange data were measured breath-by-breath and signal averaged data were fit with a monocxponential function to determine the time constants (τ). The training group showed significant increases in VO2max, (20%) and VO2 at VE(21%). The ± for oxygen uptake kinetics decreased significantly (62.2 ± 15.5 to 31.9 ± 7.0 s). The τVCO2 (70.9 ± 10.9 to 43.8 ± 11.4 s) and τVE (89.2 ± 18.0 to 50.4 ± 11.3) also were significantly faster posttraining; however, τHR (38.1 ± 20.5 to 28.6 ± 7.2) was not. significantly altered. Thus, with a vigorous training program, the kinetics of gas exchange of older individuals were faster, and approached values reported in fit young subjects.

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