Radiation Effects on DNA Synthesis and Cell Division in the Bone-marrow of the Mouse

Abstract
The radiosensitivity of C3H mouse bone-marrow was measured at various times, after a conditioning dose of 250 R by a modified method of McCulloch and Till. There was a significant variation in radiosensitivity which is explained by partial synchrony of cells after the first dose of irradiation. The validity of the specific activity measurements of bone-marrow DNA as a test for synchrony is discussed.