Predicting Outcomes after Renal Transplantation — New Tools and Old Tools

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Abstract
More than 90 percent of renal allografts transplanted today will still be functioning one year from now. This rate represents a remarkable improvement over one-year graft-survival rates of 70 percent in 1990.1 Despite this improvement in short-term success, which reflects the use of better immunosuppressive medications and the specialized management provided by the teams that care for patients with renal transplants, the long-term deficiencies of the current approaches are increasingly apparent: undesirable side effects of immunosuppressive medications and the inexorable loss of grafts due to chronic rejection. The current reality is that allograft failure is one of the four most . . .