XXXV A Caloric Test in the Monkey and its Application for Drug Evaluation

Abstract
From the data obtained with Vontrol and Dramamine, both drugs significantly reduce the duration of nystagmus for at least 2 hr. after intramuscular administration. Because of the small sample size, the statistical insignificance between the 2 drugs should not be regarded as conclusive evidence that a difference does not exist. In order to avoid the problem of large differences among the pre-drug baseline averages which complicated the statistical treatment of our data, we presently are using a randomized cross-over design to compare both drugs in the same monkey.

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