A New Approach to the Synthesis of γ-Hydroxy-α,β-unsaturated Macrolides and (−)-Pyrenophorin by Intramolecular C=C Bond Formation with Oxidative Functionalization from ω-[α-(p-Chlorophenylsulfinyl)acetoxy]alkanal

Abstract
The title compounds were prepared via the intramolecular condensation reaction of 12-[α-(p-chlorophenylsulfinyl)acetoxy]tridecanal(or dodecanal) or via the combination of inter- and intramolecular condensation of 5-[α-(p-chlorophenylsulfinyl)acetoxy]hexanal in the presence of piperidine.