Adjuvant Therapy of T1 Bladder Carcinoma: Preliminary Results of an EORTC Randomized Study

Abstract
Superficial bladder tumors (T1, P1 of the TNM Classification [19] or Jewett Stage O and A) are usually treated by transurethral resection (TUR). However, recurrence of the tumor after complete resection occurs in about 60% of the patients [9, 10] with a significant percentage of these recurrences showing a higher degree of malignancy [10]. In 10% of the cases the tumor progresses to invasive carcinoma [7] and the 5-year survival rate following TUR is about 62% [12].