A Virus Isolated from Patients Diagnosed as Non-Paralytic Poliomyelitis or Aseptic Meningitis.

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Abstract
This paper reports the isolation of a filtrable virus from the feces of patients diagnosed either as non-paralytic poliomyelitis or aseptic meningitis and from 2 patients with fever of unknown origin. The agent is characterized by producing paralysis with myositis in newborn mice. The recovery of virus was correlated with the appearance of neutralizing antibodies in the patients'' sera. At least 2 immunological types of the virus exist. The virus was widespread in the U. S. during the summer of 1948, having also been isolated from the sewage of a number of cities and from flies collected in widely separated areas. Subclinical infection may be produced in chimpanzees by oral admn. of the virus. A laboratory worker has been accidentally infected with it.

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