Enhanced Growth of Human Embryonic Cells Infected with Adenovirus 12
- 4 November 1966
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 154 (3749) , 665-667
- https://doi.org/10.1126/science.154.3749.665
Abstract
Fibroblast-like cells from human embryonic lung were infected with adenovirus type 12, and they survived as an established line, with the characteristics of "transformation" following considerable cellular killing. Inclusion bodies disappeared and cells became resistant to reinfection with type 12 virus as they grew in thick multilayered strands, and giant and syncytial cells became commonplace. An induced new cell antigen demonstrable by complement-fixation and fluorescent-antibody studies persisted for at least 20 culture passages after infection.This publication has 5 references indexed in Scilit:
- Immunofluorescence of Human Adenovirus Type 12 in Various Cell Types.Experimental Biology and Medicine, 1966
- Detection of Adenovirus Type 12 Neoantigen(s) in a Continuous Human Amnion Cell Line (FL) by Immunofluorescence.Experimental Biology and Medicine, 1965
- IMMUNOFLUORESCENT STUDIES OF ADENOVIRUS 12 TUMORS AND OF CELLS TRANSFORMED OR INFECTED BY ADENOVIRUSESThe Journal of Experimental Medicine, 1964
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