Abstract
Yeast microcolonies grown on 5 x 10 mm rectangles of membrane (Millipore) filter are treated through the membrane pores with 0.5% sodium azide for 2-3 hr, 10% perchloric acid for 4 days, and Giemsa stain for 1 day. After dehydration in air, they are permanently mounted. Similar preparations can be made with cells from sporulation cultures.

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