The Experimental Modification of Developmental Patterns in Arbacia with Malonic Acid
- 1 April 1948
- journal article
- research article
- Published by University of Chicago Press in Physiological Zoology
- Vol. 21 (2) , 100-105
- https://doi.org/10.1086/physzool.21.2.30151987
Abstract
Unfertilized eggs of Arbacia punctulata, treated for 12 hrs. with 100 cm.3 of Ca-free sea water plus 4.0 cm.3 of 0.036 [image] malonic acid, fertilized, and allowed to develop in normal sea water, were 30-40% viable. In development, cleavage rate was retarded and cleavage pattern usually irregular. Most of the eggs developed no further than slow-moving, cell-filled, irregular, bottom blastulae. Fertilized eggs (1 and 2 cells) and early blastulae exposed continuously to 100 cm.3 of Ca-free sea water plus 35 cm.3 of 0.0036 [image] malonic acid (adjusted to isotonic strength with sea water) were retarded in rate but usually developed into late gastrulae or early plutei with the basal regions strongly inhibited while the apical regions were much enlarged and extended into highly active ciliated knobs. This type of modification was attributed to differential conditioning to malonic acid.Keywords
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