Non-A Non-B Hepatitis and the Safety of Intravenous Immune Globulin, pH 4.2: A Retrospective Survey:
- 1 January 1988
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 54 (1) , 6-13
- https://doi.org/10.1111/j.1423-0410.1988.tb01605.x
Abstract
Evidence for transmission of non‐A non‐B hepatitis (NANB) was sought in 41 patients with primary immune deficiency who were receiving human intravenous immune globulin (IGIV) over periods ranging from 6 to 15 months at a monthly dosage of 400 mg/kg body weight. One lot of a reduced and alkylated IGIV and three lots of a nonmodified preparation stabilized at pH 4.2 were used. No evidence of NANB was found, although transient elevations in serum glutamic pyruvic transaminase (alanine aminotransferase) were found in 6 of the patients. The possible causes of the elevated levels in these 6 patients are discussed.This publication has 33 references indexed in Scilit:
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