Novel rifamycins. III Synthesis and antibacterial activity of 3-amidino- and of 4-aminoimidazolo(4,5-c)rifamycin derivatives.
- 1 January 1983
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 36 (11) , 1495-1501
- https://doi.org/10.7164/antibiotics.36.1495
Abstract
A number of semisynthetic rifamycin derivatives modified at position 3 and/or 4 were obtained. The synthesis and biological activities of the new compounds are described. Two compounds displayed very good antimycobacterial activity in mice.This publication has 1 reference indexed in Scilit:
- New rifamycins modified at positions 3 and 4. Synthesis, structure and biological evaluation.The Journal of Antibiotics, 1981