Inhibition of Mg, Ca-ATPase from E. coli by Ruthenium Red

Abstract
The membrane-bound, solubilized and trypsin-treated forms of Mg, Ca-ATPase from Escherichia coli are inhibited by ruthenium red[RR]. The inhibition is noncompetitive and is reduced at higher substrate concentrations. n-Butanol-extracted ATPase is not inhibited by ruthenium red and is not activated by KCl.

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