THE CONTROL OF MENINGOCOCCIC MENINGITIS EPIDEMICS

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Abstract
An epidemic of meningococcic meningitis is to be discussed in which all the present standard methods for prevention and control were given as thorough a trial as will usually be possible. A difficult problem presented itself in that cases continued to occur in spite of the application of these control measures. Active immunization against the meningococcus, which heretofore had not been used in the presence of an epidemic, was then considered as a possible means of control, and a study of a meningococcus broth culture was begun to find a product for that purpose. The filtrate of the broth culture containing a soluble toxin1was selected as a skin testing and immunizing substance and was given a trial to determine its value as a means of control in the epidemic. It is recognized that to determine its value as a protective agent it will have to be used in

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