Mucosal secretin of the duodenum in peptic ulcer disease.
- 1 January 1981
- journal article
- research article
- Published by Tohoku University Medical Press in The Tohoku Journal of Experimental Medicine
- Vol. 133 (3) , 301-305
- https://doi.org/10.1620/tjem.133.301
Abstract
Mucosal secretin content of the duodenum was measured using bioptic specimen in healthy controls and patients with peptic ulcers. Immunoreactive secretin in the duodenal mucosa was greater in healthy controls (7.73 .+-. 2.71 ng/mg dry wt (mean .+-. SD) than in gastric ulcer patients (5.76 .+-. 3.51 ng/mg dry wt) and duodenal ulcer patients (5.54 .+-. 2.48 ng/mg dry wt), but the difference was not significant. There was no significant relationship between mucosal secretin and acid output in these patients.This publication has 5 references indexed in Scilit:
- Measurement of secretin in the mucosa of digestive tract by radioimmunoassay.The Tohoku Journal of Experimental Medicine, 1980
- Effect of Graded Amounts of Acid Instilled into the Duodenum on Pancreatic Bicarbonate Secretion and Plasma Secretin in Duodenal Ulcer Patients and Normal SubjectsGastroenterology, 1977
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- In Situ ph of Duodenal Bulb Contents in Normal and Duodenal Ulcer SubjectsGastroenterology, 1967
- STUDIES IN PANCREATIC FUNCTION .5. THE USE OF THE SECRETIN TEST IN THE DIAGNOSIS OF PANCREATITIS AND IN THE DEMONSTRATION OF PANCREATIC INSUFFICIENCIES IN GASTROINTESTINAL DISORDERS1953