Enantiomeric cannabinoids: stereospecificity of psychotropic activity
- 1 September 1988
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 44 (9) , 762-764
- https://doi.org/10.1007/bf01959156
Abstract
The 1,1-dimethylheptyl homolog of (−)-(3R,4R)-7-hydroxy-delta-6-tetrahydrocannabinol (compoundII) is highly psychotropic in mice, rats and pigeons. The (+)-(3S,4S) enantiomer (III) was found to be psychotropically inactive at doses up to several thousand times those of the ED50 of (II).Keywords
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