MDM2 function
- 1 April 1998
- journal article
- review article
- Published by Elsevier in Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- Vol. 1377 (2) , M55-M59
- https://doi.org/10.1016/s0304-419x(97)00037-1
Abstract
No abstract availableKeywords
This publication has 29 references indexed in Scilit:
- p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 bindingOncogene, 1997
- Regulation of p53 stability by Mdm2Nature, 1997
- Mdm2 promotes the rapid degradation of p53Nature, 1997
- Conservation of structural domains and biochemical activities of the MDM2 protein from Xenopus laevisOncogene, 1997
- Structure of the MDM2 Oncoprotein Bound to the p53 Tumor Suppressor Transactivation DomainScience, 1996
- Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: Transforming ability and frequent detection in human cancerNature Medicine, 1996
- Mapping of the p53 and mdm-2 interaction domains.Molecular and Cellular Biology, 1993
- Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53Nature, 1993
- Amplification of a gene encoding a p53-associated protein in human sarcomasNature, 1992
- The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivationCell, 1992