Tricalcium Phosphate Crystallosis

Publisher Website
Google Scholar
Abstract
Three years of inadvertent excessive inhalation and ingestion of the dust from a dentifrice resulted in the systemic accumulation of tricalcium phosphate crystals and granulomatous lesions in a patient who died from carcinomatosis apparently unrelated to the crystallosis. Dyspnea and cough were the only symptoms. Crystals detected in the tissues by high magnification and polarized light and identified by x-ray-diffraction analysis matched those of the dentifrice, and of standard tricalcium phosphate. Continual heedless exposure to minute, insoluble, airborne crystals dispersed from widely used powdery abrasive substances may have caused other instances of systemic or pulmonic granulomas.

This publication has 0 references indexed in Scilit: