LOCAL IMMUNITY IN PIG RESPIRATORY-TRACT .2. RELATIONSHIP OF SERUM AND LOCAL ANTIBODIES

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  • 1 January 1977
    • journal article
    • research article
    • Vol. B128  (1) , 109-119
Abstract
Antibody passage from blood to respiratory secretions was studied in pigs. The animals were passively immunized and had a high anti-hog cholera serum antibody titer. With normal animals as with swine influenza animals, no serum antibody could be recovered in buccopharyngeal secretions or in lung washings; it seems that in such conditions no detectable transudation occurs from blood to local secretions. Following intranasal inoculation of swine influenza virus or i.m. injection of live attenuated hog cholera virus, local antibodies appear, which are considered to be locally produced.