Fast prediction of RNA-RNA interaction
Open Access
- 4 January 2010
- journal article
- Published by Springer Nature in Algorithms for Molecular Biology
- Vol. 5 (1) , 5
- https://doi.org/10.1186/1748-7188-5-5
Abstract
Regulatory antisense RNAs are a class of ncRNAs that regulate gene expression by prohibiting the translation of an mRNA by establishing stable interactions with a target sequence. There is great demand for efficient computational methods to predict the specific interaction between an ncRNA and its target mRNA(s). There are a number of algorithms in the literature which can predict a variety of such interactions - unfortunately at a very high computational cost. Although some existing target prediction approaches are much faster, they are specialized for interactions with a single binding site.Keywords
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