Ethnic differences in outcome of serum screening for Down's syndrome

Abstract
# Differences in median values may account for differences in false positive rates {#article-title-2} EDITOR,—Lucy Gilbert and colleagues report that serum screening for Down's syndrome had a higher false positive rate in women of Indian Asian origin than in white women.1 They speculate that racial differences in the median concentrations of the biochemical markers used may explain this finding. Evidence from our laboratory indicates that this is at least part of the reason. Samples from Indian Asian ethnic groups account for 25-30% of those …

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