Use of radioactive bleomycin to detect malignant intracranial tumors

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Abstract
✓ A new isotopic method for the detection of cerebral tumors using labeled bleomycin is described. In a series of 104 patients, bleomycin was found superior to technetium-99m for the diagnosis of intracranial metastatic lesions; in 50% of the cases, bleomycin revealed metastases undetected by the Tc-99m, particularly in the posterior fossa. This method also provides valuable data for the differentiation of gliomas from metastases.