Improved Preparation of N-(Phenylisopropyloxycarbonyl) Amino Acids from the Corresponding Fluoroformate.
- 1 January 1979
- journal article
- research article
- Published by Danish Chemical Society in Acta Chemica Scandinavica
- Vol. 33b (9) , 690-692
- https://doi.org/10.3891/acta.chem.scand.33b-0690
Abstract
2-Phenylisopropyl fluoroformate was prepared from the corresponding alcohol and carbonyl chloride fluoride. Although rather labile even at 0.degree. C, this new derivative seems an attractive intermediate for the preparation of N-(2-phenylisopropyloxycarbonyl) amino acids for peptide synthesis. This is demonstrated for a number of different amino acids.This publication has 1 reference indexed in Scilit:
- tert-BUTOXYCARBONYL-L-PROLINEOrganic Syntheses, 1973