OESTRADIOL PRODUCTION BY HUMAN GRAAFIAN FOLLICLES CULTURED IN VITRO

Abstract
Intact human Graafian follicles recovered during the preovulatory phase of the menstrual cycle and cultured in vitro, gave a mean oestradiol production of 33 ng/hour over periods of 4 to 92 hours. Treatment of follicles with human pituitary gonadotrophin or human chorionic gonadotrophin resulted in an increased production of oestradiol.