Modification of the Friend Virus Disease by Splenectomy.
- 1 August 1961
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 107 (4) , 824-828
- https://doi.org/10.3181/00379727-107-26768
Abstract
The Friend Virus syndrome in Ha/ICR Swiss is fundamentally modified by splenectomy either 3 days before or 4, 19, 21 and 27 days after inoculation of the virus. Peripheral erythroblastosis and erythrocytosis only occur in presence of the spleen. The characteristic leukocytosis is not seen up to 48 days after infection in splenectomized mice; however, leukocytosis appears again after gross hepatomegaly. Although the hemopoietic syndrome of the Friend Virus Disease is modified by splenectomy, the virus induced reticulum cell leukemia eventually appears.Keywords
This publication has 1 reference indexed in Scilit:
- Effect of Friend Virus in Swiss and DBA/1 Mice on Fe59 Uptake.Experimental Biology and Medicine, 1961