Domain Mapping Studies Reveal That the M Domain of hsp90 Serves as a Molecular Scaffold to Regulate Akt-Dependent Phosphorylation of Endothelial Nitric Oxide Synthase and NO Release
Top Cited Papers
- 3 May 2002
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 90 (8) , 866-873
- https://doi.org/10.1161/01.res.0000016837.26733.be
Abstract
Protein-protein interactions with the molecular chaperone hsp90 and phosphorylation on serine 1179 by the protein kinase Akt leads to activation of endothelial nitric oxide synthase. However, the i...Keywords
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