Serum Ferritin during Inflammation A Study on Myocardial Infarction

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Abstract
The ferritin level in serum was investigated in 9 patients with myocardial infarction, all with a history of chest pain of less than 4 h before admission. A significant rise in serum ferritin level was found in 8 patients. The rise was generally smaller than that seen in acute infection and not significantly correlated to the size of infarction, as estimated from changes in serum levels of myoglobin, ASAT [aspartate aminotransferase] and LDH [lactate dehydrogenase]. The rise started after a mean of 30 h, the peak being reached within 1 wk. Serum ferritin then fell to 120-300% of the initial level, where it remained. An initial rise in serum Fe levels was unexpectedly seen within 12 h in 7 patients.