Acute renal failure caused by extreme hyperphosphatemia after chemotherapy of an acute lymphoblastic leukemias
- 1 June 1984
- Vol. 53 (11) , 2425-2429
- https://doi.org/10.1002/1097-0142(19840601)53:11<2425::aid-cncr2820531111>3.0.co;2-r
Abstract
The authors report a documented case of hyperphosphatemia-induced nephrocalcinosis after chemotherapy of an acute lymphoblastic leukemia (ALL). Microscopic examination of the kidney showed numerous calcium deposits with concentric structure in the calyces and in the tubules. Electronic microsound analysis proved the deposits to be composed of calcium phosphate. The nephropathy mechanism is studied, and a review of the 34 similar cases of this acute tumor lysis syndrome is made. Some suggestions are put forward to present the consequences of this therapy-induced syndrome.This publication has 24 references indexed in Scilit:
- Cancer and the kidney: Renal complications of neoplasmsThe American Journal of Medicine, 1981
- Acute tumor lysis syndrome: A review of 37 patients with Burkitt's lymphomaThe American Journal of Medicine, 1980
- Extreme hyperphosphataemia causing acute anuric nephrocalcinosis in lymphosarcoma.BMJ, 1979
- Preservation of Function in Experimental Renal Disease by Dietary Restriction of PhosphateNew England Journal of Medicine, 1978
- Renal failure secondary to leukemic infiltration of the kidneysThe American Journal of Medicine, 1977
- Acute Hyperphosphatemia and Acute Persistent Renal Insufficiency Induced by Oral Phosphate TherapyAnnals of Internal Medicine, 1975
- Urologic Manifestations of Childhood LeukemiaJournal of Urology, 1972
- Hypocalcemia—a complication of childhood leukemiaCancer, 1972
- Xanthine Nephropathy in a Patient with Lymphosarcoma Treated with AllopurinolNew England Journal of Medicine, 1970
- Studies of the mechanism by which phosphate infusion lowers serum calcium concentration.Journal of Clinical Investigation, 1966