Areas under thermal-dilution curves, assuming log-normal distribution
- 1 July 1964
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 207 (1) , 144-148
- https://doi.org/10.1152/ajplegacy.1964.207.1.144
Abstract
Graphical methods are described for the calculation of areas under dilution curves. Replotting of the original curve and subsequent planimetry can be avoided by assuming log-normal distribution of the transit times. The validity of the assumption is indicated. Relative accuracies of the proposed methods are discussed. A comparison is drawn between the log-normal assumption and the negative exponential law of Hamilton, and a systematic deviation between the procedures is observed for higher values of the cardiac output. The log-normal assumption has a trend to yield higher values for the cardiac output than the classical method of Hamilton.Keywords
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