On the biosynthesis of asperlicin and the directed biosynthesis of analogs in Aspergillus alliaceus.

Publisher Website
Google Scholar
Abstract
Feeding of 14C-labeled amino acids to resting of Aspergillus alliaceus strongly supported the intuitive hypothesis that aspercilin is biosynthesized from tryptophan, anthranilate and leucine. The resting cell system was used also to prepare 25 asperlicin analogs via directed biosynthesis in presence of analogs of tryptophan and leucine.