Abstract
A NUMBER of reviews dealing with various aspects of the subject of microbial resistance to chemotherapeutic agents have appeared during recent years. Elizabeth McCoy's survey of the literature entitled "Changes in the Host Flora Induced by Chemotherapeutic Agents"1 is quite pertinent. More recently Lepper2 attempted to estimate the extent of the problem of antibiotic-resistant organisms as a cause of bacterial infections. The literature dealing with special aspects has also been considered — the problem of resistant staphylococci by Prissick,3 Spink4 and Clough,5 the genetic factors by Bryson and Szybalski6 and Bryson and Demerec,7 streptomycin resistance by Miller and Bohnhoff,8 and . . .