The fibrolamellar variant of hepatocellular carcinoma. Its association with focal nodular hyperplasia
- 15 December 1987
- Vol. 60 (12) , 3049-3055
- https://doi.org/10.1002/1097-0142(19871215)60:12<3049::aid-cncr2820601232>3.0.co;2-m
Abstract
A case of fibrolamellar hepatocellular carcinoma (FL-HCC) associated with adjacent focal nodular hyperplasia (FNH) is described. These two regions were adjacent but distinct, both on gross and microscopic examination. Currently, it is unclear whether FL-HCC rarely arises in preexisting FNH, or whether FNH is a typical response to this vascular variant of hepatocellular carcinoma (HCC). The FNH region, which is peripheral, may be biopsied to exclude the underlying carcinoma, and thus lead to inadequate therapy. Previous reports of this association are reviewed.This publication has 34 references indexed in Scilit:
- Fibrolamellar hepatocellular carcinoma.Radiology, 1985
- Fibrolamellar hepatomaThe American Journal of Surgery, 1985
- Hepatocellular carcinoma in young peopleCancer, 1983
- Hepatocellular carcinoma. Review of 32 cases in childhood and adolescenceCancer, 1983
- Fibrolamellar CarcinomaSouthern Medical Journal, 1983
- Hepatocellular Carcinoma in Women: Probable Lack of Etiologic Association With Oral Contraceptive SteroidsHepatology, 1982
- Case report. Hepatocellular carcinoma with lamellar fibrosis: An important histological variantPathology, 1981
- Hepatocellular carcinoma. Polygonal cell type with fibrous stroma—an atypical variant with a favorable prognosisCancer, 1980
- Fibrolamellar carcinoma of the liver: A tumor of adolescents and young adults with distinctive clinico-pathologic featuresCancer, 1980
- Focal nodular hyperplasia and liver cell adenoma: radiologic and pathologic differentiationAmerican Journal of Roentgenology, 1978