Transformation by Cloned Harvey Murine Sarcoma Virus DNA: Efficiency Increased by Long Terminal Repeat DNA
- 12 December 1980
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 210 (4475) , 1249-1251
- https://doi.org/10.1126/science.6254153
Abstract
The coding sequences for the transforming (src) protein (p21) of Harvey murine sarcoma virus have been localized to a 1.3 kilobase pair segment near the 5' end of the viral genome. Ligation of the viral terminal repeat DNA to the left end of the src region DNA markedly enhanced the low transforming efficiency of the src region DNA.This publication has 29 references indexed in Scilit:
- Identification of a normal vertebrate cell protein related to the p21 src of harvey murine sarcoma virusVirology, 1980
- Transformation by subgenomic fragments of Rous sarcoma virus DNACell, 1980
- Properties of a Normal Mouse Cell DNA Sequence (sarc) Homologous to the src Sequence of Moloney Sarcoma VirusScience, 1980
- The transforming gene of Moloney murine sarcoma virusNature, 1979
- In vitro synthesis of a 9 kbp terminally redundant DNA carrying the infectivity of moloney murine leukemia virusCell, 1979
- Restriction endonuclease cleavage of linear and closed circular murine leukemia viral DNAS: Discovery of a smaller circular formCell, 1979
- A defined subgenomic fragment of in vitro synthesized Moloney sarcoma virus DNA can induce cell transformation upon transfectionCell, 1979
- Mapping unintegrated avian sarcoma virus DNA: Termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNACell, 1978
- Characterization of a normal avian cell protein related to the avian sarcoma virus transforming gene productCell, 1978
- Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sitesCell, 1978