ALKALINE AND ACID-PHOSPHATASE ACTIVITY IN LIVER AND SERUM IN NI AND FE DEFICIENCY

  • 1 January 1977
    • journal article
    • research article
    • Vol. 47  (3) , 274-276
Abstract
During studies on the essentiality of Ni, a reduced Fe absorption causing anemia was observed. Since Ni deficiency affects Zn metabolism, the different phosphatase activities were determined in [rat] liver and serum. Ni deficiency, resulted in an increased activity of the alkaline phosphatase in liver. The activity of the alkaline phosphatase was deduced by 59% during Fe deficiency. The alkaline and acid phosphatases in serum were reduced during Fe deficiency. Determination of activity of the alkaline phosphatase in serum, besides that of various liver enzymes, is suited well to differentiate between Fe and Ni deficiency.

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