Analytical precautions in measurement of blood cyanide.
- 1 December 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 24 (12) , 2184-2185
- https://doi.org/10.1093/clinchem/24.12.2184
Abstract
Solutions of KCN in 0.1 mol/liter NaOH, stored for six months at 4 degrees C, were unchanged as determined by silver titration and color development with pyridine-pyrazalone reagent. At room temperature the cyanide concentration of such solutions decreased by 0.079% per day (half life = 880 days) and the extent of color development changed in direct proportion to the change in silver titer. Rubber stoppers adsorb (or dissolve) HCN when in contact with this gas. The cyanide tends to come out of the stopper long after the source of the gas is removed. Rubber stoppers and expired air contaminated by HCN must be carefully avoided during cyanide analysis. Expired air contains HCN, generally in larger amounts for persons who smoke.This publication has 3 references indexed in Scilit:
- Determination of cyanide and nitroprusside in blood and plasma.Clinical Chemistry, 1977
- Standardization of hemoglobinometry II. The hemiglobincyanide methodClinica Chimica Acta; International Journal of Clinical Chemistry, 1961
- Determination of traces of hydrogen cyanide in respiratory airArchives of Biochemistry and Biophysics, 1952