Abstract
In view of the fact that so little definite information concerning the importance of familial syphilitic infection in paresis has been brought before the American medical public, it has been thought desirable to present briefly certain observations which we have been able to make in this connection during the past three years. The material on which our observations have been made includes, first, fifty-five clinically unquestionable cases of general paralysis in married individuals admitted during this time in which we have been able to test the presence of syphilitic infection in the other mate, and secondly, eighty-six cases in which the anamnesis concerning intimate family matters of absolute sterility, pregnancies with early abortions, total number of living-born children, with additional abortions, miscarriages, etc., could be accepted without question. We have been able to examine the blood serum of the conjugal mate in fifty-three married paretics. Seventeen, or 32.7 per cent.,

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