Administration of Cortisone by the Aerosol Method in the Treatment of Bronchial Asthma

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Abstract
THE administration of drugs by the aerosol method in the treatment of diseases of the bronchopulmonary tree has long been an accepted mode of therapy. In bronchial asthma, bronchodilators and antibiotics of all sorts have proved extremely beneficial when applied in this manner.1 2 3 4 5 6 7 Recently cortisone has been shown to have a definitely favorable therapeutic effect in bronchial asthma.8 9 10 11 It has been given both intramuscularly and orally with equal success. There are, however, no reports to date of the application of cortisone directly to the pulmonary epithelium in the treatment of bronchial asthma. Reeder and Mackey's demonstration12 that nebulized cortisone delivered . . .