Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans
- 1 September 1999
- journal article
- Published by Wiley in The FASEB Journal
- Vol. 13 (12) , 1532-1536
- https://doi.org/10.1096/fasebj.13.12.1532
Abstract
Mitochondrial DNA (mtDNA) is characterized by high variability, maternal inheritance, and absence of recombination. Studies of human populations have revealed ancestral associated polymorphisms who...Keywords
Funding Information
- Regione Calabria
- Ministero della Salute
This publication has 20 references indexed in Scilit:
- Gene/longevity association studies at four autosomal loci (REN, THO, PARP, SOD2)European Journal of Human Genetics, 1998
- Mitochondrial genotype associated with longevityThe Lancet, 1998
- Genetic modulation of the senescent phenotype of Homo SapiensExperimental Gerontology, 1996
- MOLECULAR GENETIC ASPECTS OF HUMAN MITOCHONDRIAL DISORDERSAnnual Review of Genetics, 1995
- Human aging is associated with stochastic somatic mutations of mitochondrial DNAMutation Research/DNAging, 1995
- Mitochondrial Genetics: A Paradigm for Aging and Degenerative Diseases?Science, 1992
- Family patterns of coronary heart disease mortality: The Framingham Longevity StudyJournal of Clinical Epidemiology, 1992
- No Adjustments Are Needed for Multiple ComparisonsEpidemiology, 1990
- Sequence and organization of the human mitochondrial genomeNature, 1981
- Maternal inheritance of human mitochondrial DNA.Proceedings of the National Academy of Sciences, 1980