Evidence that spontaneous mitotic recombination occurs at the two-strand stage.
- 1 September 1978
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 75 (9) , 4436-4440
- https://doi.org/10.1073/pnas.75.9.4436
Abstract
Spontaneous reciprocal mitotic recombination in the yeast Saccharomyces cerevisiae, associated with heteroallelic recombination, occurs almost exlusively at the 2-strand stage and involves recombination of unduplicated chromosomes (i.e., during GI) or the unduplicated regions of chromosomes during the S phase of mitosis. The associated heteroallelic recombination frequently reflects the formation of symmetric Holliday structures, is not strongly polarized with respect to conversion at the heteroallelic trp5 sites studies, occasionally results in simultaneous conversion of widely separated genetic markers, and is positively correlated with recombination of flanking markers.This publication has 4 references indexed in Scilit:
- Evidence for joint genic control of spontaneous mutation and genetic recombination during mitosis inSaccharomycesMolecular Genetics and Genomics, 1977
- A general model for genetic recombination.Proceedings of the National Academy of Sciences, 1975
- Studies of Gene Mutation in SaccharomycesPublished by Cold Spring Harbor Laboratory ,1956