The differing responses of four muscle types to dexamethasone treatment in the rat
- 15 October 1982
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 208 (1) , 147-151
- https://doi.org/10.1042/bj2080147
Abstract
The glucocorticoid dexamethasone dramatically altered growth patterns in 4 muscle types, inducing atrophy of smooth and fast-twitch skeletal muscle, suppressing protein accumulation of slow-twitch muscle and enhancing heart growth. These differing responses were explained by steroid-induced changes in RNA content, protein synthesis and protein breakdown.This publication has 24 references indexed in Scilit:
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