Dealing with Discounting: An Application to the Cost-Effectiveness of Intracoronary Thrombolysis with Streptokinase

Abstract
By introducing discounting in the DEALE method, we reanalyze a recent publication on the cost-effectiveness of early thrombolytic therapy with intracoronary streptokinase after acute myocardial infarction. We show that failure to discount gains in life expectancy results in a serious overestimation of the cost-effectiveness of this technology.

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