Wegener's Granulomatosis, Immunosuppressive Therapy

1 January 1976

journal article
research article
Published by Taylor & Francis in Acta Oto-Laryngologica

Vol. 82 (1-6) , 208-211
https://doi.org/10.3109/00016487609120885

Abstract

We present a study of 11 patients with We-gener's granulomatosis. Seven of these were treated with Azathioprine (Imurel) combined with prednisone. Of these, 4 patients rapidly improved after the treatment was started. Atelectatic changes in the lungs disappeared. A rapidly progressive renal failure was reversed, and renal function returned to normal. Large lesions of the skin also improved. The treatment has now lasted 21/2–41/2 years without interruption. We have not had any serious side effects due to Imurel. We believe that the good effect of the treatment is due to immunosuppression by the drugs.

Keywords

This publication has 4 references indexed in Scilit:

Non-healing granulomata of the upper respiratory tract.
BMJ, 1974
IMMUNOLOGICAL FEATURES OF WEGENER'S GRANULOMATOSIS
The Lancet, 1974
Wegener's Granulomatosis
Radiology, 1973
IMMUNOSUPPRESSIVE THERAPY IN WEGENER'S GRANULOMATOSIS
Acta Medica Scandinavica, 1970