From Birth to Death: The Complex Lives of Eukaryotic mRNAs
Top Cited Papers
- 2 September 2005
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 309 (5740) , 1514-1518
- https://doi.org/10.1126/science.1111443
Abstract
Recent work indicates that the posttranscriptional control of eukaryotic gene expression is much more elaborate and extensive than previously thought, with essentially every step of messenger RNA (mRNA) metabolism being subject to regulation in an mRNA-specific manner. Thus, a comprehensive understanding of eukaryotic gene expression requires an appreciation for how the lives of mRNAs are influenced by a wide array of diverse regulatory mechanisms.Keywords
This publication has 44 references indexed in Scilit:
- Ribo-gnome: The Big World of Small RNAsScience, 2005
- Localization of all seven messenger RNAs for the actin-polymerization nucleator Arp2/3 complex in the protrusions of fibroblastsJournal of Cell Science, 2005
- SRprises along a Messenger’s JourneyMolecular Cell, 2005
- Nuclear export of RNABiology of the Cell, 2004
- eIF4G is required for the pioneer round of translation in mammalian cellsNature Structural & Molecular Biology, 2004
- Splicing of oskar RNA in the nucleus is coupled to its cytoplasmic localizationNature, 2004
- Structural Basis of Single-Stranded RNA RecognitionAccounts of Chemical Research, 2004
- Extensive Association of Functionally and Cytotopically Related mRNAs with Puf Family RNA-Binding Proteins in YeastPLoS Biology, 2004
- Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamicsNature Reviews Molecular Cell Biology, 2004
- The Role of the Cap Structure in RNA Processing and Nuclear ExportEuropean Journal of Biochemistry, 1997