Effects of Ionizing Radiation and Cysteamine (MEA) on Activity of Mouse Spleen Adenyl Cyclase
- 1 January 1976
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 29 (6) , 549-553
- https://doi.org/10.1080/09553007614550651
Abstract
In mice X-irradiated with doses of 200 R and 400 R, there was a substantial increase in spleen adenyl cyclase activity; there was similar activation by MEA. In mice given MEA before irradiation, an additive effect of radiation and the radioprotective drug was observed. On the other hand, a dose of 800 R given either alone or after pre-treatment with MEA failed to elicit any change in cyclase activity. The results indicate the importance of the adenyl cyclase system in the response of cells to irradiation and action of MEA.This publication has 17 references indexed in Scilit:
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