JC virus genotyping offers a new paradigm in the study of human populations
- 27 April 2004
- journal article
- review article
- Published by Wiley in Reviews in Medical Virology
- Vol. 14 (3) , 179-191
- https://doi.org/10.1002/rmv.428
Abstract
A small DNA virus, named JC virus (JCV) and belonging to the Polyomaviridae, is attracting the attention of anthropologists worldwide, as JCV genotyping appears to be a novel means of elucidating human migrations and the origins of various ethnic groups. The basic properties of JCV, the regional distributions of JCV genotypes, and the phylogenetic relationships among various JCV genotypes are described. Then, a study is described in which the origin of the modern Japanese was extensively investigated using the JCV genotyping method. Based on JCV genotypes in neighboring areas, the origins of people who carried JCV genotypes to the Japanese Archipelago are discussed. Finally, the relationships between JCV genotypes and Y‐chromosome haplogroups are examined, as genetic variation on the Y chromosome has recently been examined in detail to investigate ancient human migrations and the population structures of human groups. Copyright © 2004 John Wiley & Sons, Ltd.Keywords
This publication has 74 references indexed in Scilit:
- High-Resolution SNPs and Microsatellite Haplotypes Point to a Single, Recent Entry of Native American Y Chromosomes into the AmericasMolecular Biology and Evolution, 2003
- The human Y chromosome: an evolutionary marker comes of ageNature Reviews Genetics, 2003
- Reduced Y-Chromosome, but Not Mitochondrial DNA, Diversity in Human Populations from West New GuineaAmerican Journal of Human Genetics, 2003
- Phylogenetic Analysis of JC Virus DNAs Detected in Ainus: An Attempt to Elucidate the Origin and Diversity of the AinuAnthropological Science (Japanese Series), 2003
- Peopling of Myanmar as Demonstrated by Genotyping of Urinary JC Virus DNA.Anthropological Science, 2002
- New JC virus (JCV) genotypes from Papua New Guinea and Micronesia (Type 8 and Type 2E) and evolutionary analysis of 32 complete JCV genomesArchiv für die gesamte Virusforschung, 2001
- Paternal Population History of East Asia: Sources, Patterns, and Microevolutionary ProcessesAmerican Journal of Human Genetics, 2001
- Five complete genomes of JC virus Type 3 from Africans and African AmericansArchiv für die gesamte Virusforschung, 1997
- Population history of Japan as viewed from cranial nonmetric variation.Journal of the Anthropological Society of Nippon, 1990
- Mitochondrial DNA and human evolutionNature, 1987