Statistical analysis of data bearing on the number of particles required to form a plaque
- 1 August 1974
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 73 (1) , 27-34
- https://doi.org/10.1017/s0022172400023792
Abstract
Methods of statistical analysis are presented for one or more dilution series experiments where the quantity of interest is the number of virus particles required to infect a cell. These methods are illustrated on several data sets drawn from the literature. Data from seven series, which have been used to support a two-particle model in the literature, are here shown to reject such a model decisively, whereas fifteen other experiments are found to be in excellent agreement with a one-particle model.Keywords
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