iProClass: an integrated, comprehensive and annotated protein classification database
Open Access
- 1 January 2001
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 29 (1) , 52-54
- https://doi.org/10.1093/nar/29.1.52
Abstract
The iProClass database is an integrated resource that provides comprehensive family relationships and structural and functional features of proteins, with rich links to various databases. It is extended from ProClass, a protein family database that integrates PIR superfamilies and PROSITE motifs. The iProClass currently consists of more than 200 000 non-redundant PIR and SWISS-PROT proteins organized with more than 28 000 superfamilies, 2600 domains, 1300 motifs, 280 post-translational modification sites and links to more than 30 databases of protein families, structures, functions, genes, genomes, literature and taxonomy. Protein and family summary reports provide rich annotations, including membership information with length, taxonomy and keyword statistics, full family relationships, comprehensive enzyme and PDB cross-references and graphical feature display. The database facilitates classification-driven annotation for protein sequence databases and complete genomes, and supports structural and functional genomic research. The iProClass is implemented in Oracle 8i object-relational system and available for sequence search and report retrieval at http://pir.georgetown.edu/iproclass/ .Keywords
This publication has 16 references indexed in Scilit:
- Protein Information Resource: a community resource for expert annotation of protein dataNucleic Acids Research, 2001
- The MetaFam Server: a comprehensive protein family resourceNucleic Acids Research, 2001
- The RESID Database of protein structure modifications: 2000 updateNucleic Acids Research, 2000
- ProClass protein family databaseNucleic Acids Research, 2000
- The COG database: a tool for genome-scale analysis of protein functions and evolutionNucleic Acids Research, 2000
- ProDom and ProDom-CG: tools for protein domain analysis and whole genome comparisonsNucleic Acids Research, 2000
- The Pfam Protein Families DatabaseNucleic Acids Research, 2000
- Increased coverage of protein families with the Blocks Database serversNucleic Acids Research, 2000
- PRINTS-S: the database formerly known as PRINTSNucleic Acids Research, 2000
- PIR-ALN: a database of protein sequence alignments.Bioinformatics, 1999