In-vitro activity of Sch 34343, a new penam, against Gram-positive isolates from cancer patients
Open Access
- 1 August 1986
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 18 (2) , 159-162
- https://doi.org/10.1093/jac/18.2.159
Abstract
The in-vitro activity of Sch 34343, a new penam antibiotic, was tested against 257 Gram-positive isolates from cancer patients, and compared with that of imipenem and amifloxacin. Sch 34343 was extremely active against β-haemolytic streptococci (Lancefield groups A, B and G) with MIC90s ranging from 0.025 to 0.05 mg/l. It was also active against methicillin-susceptible Staphylococcus aureus and had variable activity against coagulase-negative staphylococci. MIC90 for Listeria monocytogenes was 0.78 mg/l and 84% of enterococcal isolates were inhibited by 6.25 mg/l.Keywords
This publication has 2 references indexed in Scilit:
- In vitro activity of Sch 34343 and cefbuperazone against anaerobic bacteriaAntimicrobial Agents and Chemotherapy, 1985
- Staphylococcus epidermidis: An Increasing Cause of Infection in Patients with GranulocytopeniaAnnals of Internal Medicine, 1982