Characterization of a Neutral Polysaccharide Having Activity on the Reticuloendothelial System from the Rhizome of Curcuma longa.
- 1 January 1992
- journal article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 40 (1) , 185-188
- https://doi.org/10.1248/cpb.40.185
Abstract
A neutral polysaccharide, named ukonan D, was isolated from the rhizome of Curcuma longa L. It produced a single hand on electrophoresis and a single peak on gel chromatography, and its molecular mass was estimated to be 28000. It showed remarkable reticuloendothelial system-potentiating activity in a carbon clearance test. Ukonan D is composed of L-arabinose : D-galactose : D-glucose : D-mannose in the molar ratio of 1 : 1 : 12 : 0.2, in addition to small amounts of peptide moiety. Methylation analysis, carbon-13 nuclear magnetic resonance and enzymic degradation studis indicated that its structural features include mainly both α-1, 5-linked L arabino-β-3, 6-branched D-galactan type and α-4, 6-branched D-glucan type structural units. The influence of degradation with α-amylase followed by the elimination of glucan side chains on its immunological activity was discussed.Keywords
This publication has 0 references indexed in Scilit: