Putting the Brakes on Cylindromatosis?
- 8 January 2004
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 350 (2) , 187-188
- https://doi.org/10.1056/nejmcibr032650
Abstract
A recent study shows that the gene that is mutated in familial cylindromatosis represses tumor necrosis factor α (TNF-α) signaling — a finding that may have implications for preventing the disease.Keywords
This publication has 4 references indexed in Scilit:
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- CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family membersNature, 2003
- The tumour suppressor CYLD negatively regulates NF-κB signalling by deubiquitinationNature, 2003
- Identification of the familial cylindromatosis tumour-suppressor geneNature Genetics, 2000